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Dr.Kazuhisa Honda
Kobe University
Title: Regulation of feed intake and body fat mass in chickens




Kazuhisa Honda is an Associate Professor at the Graduate School of Agricultural Science at Kobe University, Japan. He completed his master degree at Kobe University in 1993, following which he held a research position at the Central Research Institute of Itoham Food Inc. from 1993 to 2001. After obtaining his PhD from Kagoshima University in 2001, he switched to a new career and joined the Department of Bioresource Science within the Graduate School of Agricultural Science at Kobe University as an Assistant Professor. Here, he was further promoted to the rank of Associate Professor in 2013. His research mainly focuses on improving abdominal fat accumulation and lipid metabolism in chickens. He studies the molecular mechanisms that regulate their feed intake, and has proposed several physiological roles of neuropeptides and peripheral hormones such as neuropeptide Y, proopiomelanocortin (POMC)-derived melanocortin peptides, glucagon-related peptides, neuromedin U, peptide YY, and insulin in the regulation of feed intake in broiler and layer chicks. His reports suggest that glucagon-like peptide (GLP)-1 and GLP-2, which are proglucagon-derived brain-gut peptides, play important roles in the regulation of feed intake, not only in the central nervous system but also in peripheral circulation in chickens. His studies also suggest that the melanocortin peptide alpha-melanocyte stimulating hormone (-MSH) functions as a powerful anorexigenic neuropeptide in the brain of chicks, in contrast to other melanocortin peptides such as -MSH and -MSH. His work has also focused on the identification of regulatory mechanisms underlying the transcription of key enzymes in triacylglycerol and fatty acid metabolism in the liver and abdominal adipose tissue of chicks. The results of his studies clearly demonstrate that the mRNA levels of lipid metabolism-related genes are altered in response to feeding conditions within a few hours. All his findings have revealed species-specificity in the regulation of feed intake and lipid metabolism between mammals and birds. He has additional interests in the field of feed science, especially in the development and use of functional feed ingredients. The results of his studies have contributed to the development of commercial products such as coenzyme Q10-enriched eggs. In 2015, he was awarded by the Japanese Society of Animal Science, acknowledging his contribution to the outstanding development of animal science and the animal industry in the last 5 years. He is a member of the World Poultry Science Association, Japan Poultry Science Association, Japanese Society of Animal Science, and the Japan Society of Nutrition and Food Science, as well as a Section Editor for the Journal of Poultry Science (Nutrition and Feeds Section).

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